What is the maximum number of refills allowed for CIII-CV medications?

For controlled substances listed as Schedule III through V (CIII to CV), federal regulations permit a maximum of five refills within a six-month period from the date the prescription is issued. This means that patients may receive their medication over the course of six months, as long as the prescribing physician provides the appropriate authorization for the refills. This guideline is designed to allow patients ongoing access to medications that may be necessary for their treatment while also maintaining safeguards against misuse.

In the context of this question, the option that states five refills in six months accurately reflects the regulations established by the Drug Enforcement Administration (DEA) and is aligned with the broader understanding of pharmaceutical practice regarding controlled substances. It is essential for pharmacists and healthcare providers to adhere to these regulations to ensure compliance and patient safety.