What is included in the definition of hazardous drugs according to USP 800?

The definition of hazardous drugs according to USP 800 includes those drugs that possess certain risks, particularly those that have been identified as exhibiting carcinogenicity and teratogenicity. Carcinogenic drugs are those known to cause cancer, while teratogenic drugs are capable of causing developmental malformations in a fetus. This classification is crucial because it emphasizes the need for specific handling precautions to protect healthcare workers and patients from harmful effects associated with these drugs.

The inclusion of drugs with these properties is a key aspect of USP 800, which focuses on the safe handling of hazardous drugs to minimize exposure risks. Therefore, identifying drugs based on their carcinogenic and teratogenic potential aligns with the overarching goal of the standards set by USP 800 to ensure a safe environment for pharmacy and healthcare environments.

This understanding is pivotal for pharmacy practice, especially for those involved in compounding, dispensing, and managing medications that may pose risks to health.