How often is PIC registration required for renewal?

In Iowa, the registration of a Pharmacist-in-Charge (PIC) must be renewed annually. This requirement ensures that the PIC is actively maintaining their qualifications and is responsible for the operations within the pharmacy. The annual renewal schedule aligns with the state's pharmacy regulations, which are designed to promote safe and effective pharmaceutical practices. By requiring a yearly renewal, the state can effectively monitor the competencies and compliance of the PIC with current laws and regulations, which ultimately supports public health and safety. Therefore, the correct answer reflects the requirement of annual renewal for PIC registration.